Nutritional-toxicological conflict of fish consumption (PODO)

Nutritional-toxicological conflict of fish consumption: A tool for combined intake assessment

Marine foods represent a unique source of long chain omega-3 poly-unsaturated fatty acids (LC n-3 PUFA). But this favourable health perception of marine foods is troubled by the presence of chemical contaminants, e.g. mercury, PCBs, and dioxin-like substances. This overall dichotomous picture on marine foods forms the basis for an important conflictuous model between dietary recommendations and toxicological safety assurance. Therefore, a quantitative, probabilistic intake assessment of selected nutrients (omega-3 LC- PUFA and vitamin D) and contaminants (mercury, PCBs, and dioxins) via seafood is undertaken. A software program was developed, called ProbIntakeUG, to execute probabilistic simulations. This program combines each data point out of a consumption database with concentration data of multiple compounds (nutrients and contaminants) in order to calculate a combined intake assessment. The model can be used for real intake assessments, as well as for scenario analyses. The simulations result in multidimensional scatter plots, useful to describe the intake of the different chemicals and for a risk-benefit analysis.

Project duration: 2003-01-01 - 2007-12-30

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Isabelle Sioen
Department of Applied Mathematics, Biometrics and Process Control
Coupure Links 653
9000 Gent
Tel: ++32 9 264 9903
Fax: ++32 9 264 6215

Last update: 01 december 2008,

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